5-ALA benzyl ester hydrochloride 是原卟啉前体,可用作光检测剂。
产品描述
5-ALA benzyl ester hydrochloride is a protoporphyrin precursor and can be used as a photodetection agent.
体外活性
In colon carcinoma cell lines SW480, 5-ALA benzyl ester hydrochloride (0.6-0.12 mM; 3h) induces PPIX accumulation[1].
体内活性
In female CBA/Gy mice, 5-ALA benzyl ester hydrochloride (31 mg/kg; i.v.; 1h) results in a dose-dependent reduction in tumour porphyrin levels[2].
动物实验
Animal Model: Female CBA/Gy mouse (CaNT tumour model)
Dosage: 31 mg/kg
Administration: i.v. ; 1 hours [3]
Cas No.
163271-32-7
分子式
C12H16ClNO3
分子量
257.71
别名
Benzyl-ALA hydrochloride
储存和溶解度
DMSO:250 mg/mL (970.08 mM),Need ultrasonic
H2O:95 mg/mL (368.63 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years