产品描述
Etilevodopa is an ethyl-ester prodrug of Levodopa which is used for the treatment of Parkinson's disease (PD). It is rapidly hydrolyzed to Levodopa and ethanol by nonspecific esterases in the gastrointestinal tract. Levodopa is the direct precursor of dopamine.
体外活性
Etilevodopa passes unchanged through the stomach to the duodenum and is subsequently absorbed into the bloodstream as Levodopa [1]. Etilevodopa has a greater solubility in the stomach, faster passage to the small intestine, and a shortened time to maximum Levodopa concentration, compared with standard Levodopa [2].
Cas No.
37178-37-3
分子式
C11H15NO4
分子量
225.24
别名
L-DOPA ethyl ester;Levodopa ethyl ester
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years