Eltoprazine dihydrochloride 是一种先前开发用于攻击性的药物,最近已在帕金森病 (PD) 的动物模型和运动障碍 PD 患者中研究了左旋多巴诱导的运动障碍。
产品描述
Eltoprazine dihydrochloride is a drug that had previously been developed for aggression, has recently been investigated for L-DOPA-induced dyskinesia in animal models of Parkinson′s disease (PD) and in dyskinetic PD patients.
体外活性
In the elevated plus maze eltoprazine increased anxiety?like behavior.?On the other hand, it induced a clear?cut anxiolytic effect in context fear conditioning test starting at ca. 0.3 mg/kg[1]
Cas No.
143485-51-2
分子式
C12H18Cl2N2O2
分子量
293.19
储存和溶解度
DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years