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Bretylium tosylate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Bretylium tosylate图片
CAS NO:61-75-6
包装与价格:
包装价格(元)
2 mg电议
5 mg电议
10 mg电议
50 mg电议
100 mg电议
200 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
托西溴苄铵
溴苄乙胺
产品介绍
Bretylium tosylate 是交感神经和肾上腺素神经的阻断剂,是血管收缩的神经递质突触前释放的抑制剂。

产品描述

Bretylium tosylate is an inhibitor of the presynaptic release of vasoconstrictor neurotransmitters, a available antiarrhythmic drug for ventricular arrhythmias.

体内活性

Nine patients who had recurrent ventricular fibrillation following acute myocardial infarction or angina were given bretylium tosylate in a dose of 5 mg./kg. intramuscularly every eight hours after other measures had proved ineffective. Provided the patients were not in shock or in heart failure, there was a considerable reduction in the episodes of ventricular fibrillation.A second group of nine patients who developed recurrent ventricular fibrillation following open heart surgery were given bretylium intravenously, which controlled the arrhythmia in every instance.Bretylium did not completely abolish ventricular premature beats but the latter did not initiate ventricular fibrillation even when they occurred on the T wave[1].

Cas No.

61-75-6

分子式

C18H24BrNO3S

分子量

414.36

别名

托西溴苄铵;溴苄乙胺

储存和溶解度

DMSO:30 mg/mL (72.40 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years