ACA-28 (compound 2a) 是一种有效的ERK MAPK信号调节剂。ACA-28 通过 ERK 过度激活诱导凋亡，选择性抑制癌细胞生长。ACA-28 抑制黑色素瘤细胞 (SK-MEL-28) 和正常黑色素细胞 (NHEM) 生长，IC50值分别为 5.3 和 10.1 μM。

ACA-28 (compound 2a) is a potent ERK MAPK signaling modulator. ACA-28 selectively inhibits cancer cell growth by inducing apoptosis with ERK hyperactivation ACA-28 inhibits cell growth of melanoma cells (SK-MEL-28) and normal melanocytes (NHEM), with IC 50 values of 5.3 and 10.1 μM, respectively [1].

948044-25-5

C17H16O6

316.31

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years