4-Methoxyphenol 是一种Mercurialis spp的生物活性成分,常用于皮肤褪色。
产品描述
Leucobasal is a synthetic derivate of hydroquinone and depigmenting agent. Although the exact mechanism of the depigmenting effects of mequinol remains unclear, it may exert its effect by oxidation of tyrosinase to cytotoxic products in melanocytes.
体内活性
Leucobasal可在美国以2%的浓度,在商业上作为皮肤美白处方销售。 Leucobasal是一种酪氨酸酶的底物,从而作为竞争性抑制剂的黑素前体的形成。Leucobasal在培养基中稀释或局部使用在RE的顶部,导致色素沉着减少,转移人角质形成细胞和黑素细胞具有减少的黑色素。 Leucobasal诱导的多巴阳性黑素细胞计数的减少。
Cas No.
150-76-5
分子式
C7H8O2
分子量
124.139
别名
4-Hydroxyanisole;4-Methoxyphenol;Leucobasal;对苯二酚单甲醚
储存和溶解度
H2O:23 mg/mL (185.3 mM)
Ethanol:24 mg/mL (193.3 mM)
DMSO:24 mg/mL (193.3 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years