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Quercetin dihydrate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Quercetin dihydrate图片
CAS NO:6151-25-3
包装与价格:
包装价格(元)
50 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
Sophoretin
槲皮素
产品介绍
Quercetin dihydrate 是一种黄酮类天然产物,可激活或抑制许多蛋白质的活性。它可激活SIRT1,也可抑制PI3K,抑制 PI3K γ、PI3K δ和PI3K β 的IC50值分别为 2.4 μM、3.0 μM和 5.4 μM。

产品描述

Quercetin is a polyphenolic flavonoid that was found in a wide variety of plant-based foods, such as apples, onions, berries, and red wine. It is used for their nervous system and anticancer effects.

体外活性

Quercetin, a polyphenolic flavonoid found in a wide variety of plant-based foods, such as apples, onions, berries, and red wine, is utilized in many different cultures for their nervous system and anticancer effects. The pharmacological activities of quercetin that modulate antioxidation/oxidation/kinase-signaling pathways might be differentially elicited in neurons compared with malignant cells, ultimately promoting cell survival or death in a cell type- and metabolism-specific manner. Whereas the broad antioxidation and anti-inflammatory activities of quercetin are important for neuronal survival, the oxidative, kinase- and cell cycle-inhibitory, apoptosis-inducing effects of quercetin are essential for its anticancer effects. [1]

体内活性

LD50: Mice 159 mg/kg (i.g.) [2]

Cas No.

6151-25-3

分子式

C15H10O7·2H2O

分子量

338.27

别名

Sophoretin;槲皮素

储存和溶解度

DMSO:62 mg/mL (183.3 mM)
Ethanol:15 mg/mL(44.3 mM)
H2O:<1 mgml
Powder: -20°C for 3 years
In solvent: -80°C for 2 years