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Guanfu base I
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Guanfu base I图片
CAS NO:110225-59-7
包装与价格:
包装价格(元)
100 mg电议
500 mg电议

产品名称
Acorine
产品介绍

产品描述

Guanfu base I is an active metabolite of Guanfu base A, isolated from Aconitum coreanum. It have a potent anti-arrhythmic effect.

体内活性

The pharmacokinetics of Guanfu base I in Sprague-Dawley rats is examined.?The method is linear in the 0.05-20 μg/mL concentration range.?The recovery of Guanfu base I is more than 80%.?The intraday and interday precision, expressed as the relative standard deviation, is generally good.?After intravenous injection dosing, plasma Guanfu base I concentration declined in a bi-phasic manner with a terminal elimination half-life of 2.49 hours.?The total plasma clearance value is 1.46 L/h/kg.?After oral dosing, the plasma Guanfu base I concentration reached a maximum within 0.5 hour.?The absolute bioavailability of Guanfu base I is 71.31%.

Cas No.

110225-59-7

分子式

C22H29NO5

分子量

387.47

别名

Acorine

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years