Amodiaquin dihydrochloride (trade names Camoquin, Flavoquine) is a potent and orally bioactive inhibitor of the Ebola virus, acts by targeting the viral protein 35 (VP35). It is also a 4-aminoquinoline class of antimalarial agent and anti-inflammatory agent that inhibits histamine N-methyltransferase inhibitor. Amodiaquine is also a Nurr1 agonist and specifically binds to Nurr1-LBD (ligand binding domain) with an EC50 of ~20 μM. Amodiaquine has been shown to be more effective than chloroquine in treating chloroquine-resistant Plasmodium falciparum malaria infections and may give more protection than chloroquine when used as weekly prophylaxis. Amodiaquine, like chloroquine, is generally well tolerated. Amodiaquine is a histamine N-methyltransferase inhibitor. It is on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system.

纯度：≥98%

CAS：6398-98-7