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Resolvin E2
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Resolvin E2图片
CAS NO:865532-70-3
包装:5 mg
市场价:7000元

产品介绍

产品描述

Resolvin E2 (RvE2) is a member of the specialized pro-resolving mediator (SPM) family of bioactive lipids.1It is produced from eicosapentaenoic acidviaan 18-HEPE intermediate, which is formed by aspirin-acetylated COX-2-mediated oxidation of EPA, by 5-lipoxygenase (5-LO) in human polymorphonuclear (PMN) neutrophils.2,3RvE2 (20 ng/animal) inhibits increases in inflammatory exudate neutrophil infiltration in a mouse model of peritonitis induced by zymosan A .3Hepatic RvE2 levels are increased in mice fed normal chow, as well as in a mouse model of high-fat diet-induced non-alcoholic fatty liver disease (NAFLD), by dietary supplementation with EPA.4Plasma levels of RvE2 are increased by dietary supplementation with fish oil containing ω-3 polyunsaturated fatty acids (PUFAs) in patients with peripheral artery disease or chronic kidney disease.1,5,6

Cas No.

865532-70-3

分子式

C20H30O4

分子量

334.45

储存和溶解度

Ethanol:1 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years