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GSK319347A
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
GSK319347A图片
CAS NO:862812-98-4
包装:10 mg
市场价:7781元

产品介绍

产品描述

GSK319347A is a TBK1 and IKKε dual inhibitor (IC50s: 93 nM and 469 nM, respectively). GSK319347A inhibits IKK2 (IC50: 790 nM).

体外活性

IKK-3 Inhibitor exhibits excellent selectivity against cell-cycle kinases CDK2 and AurB[1]. GSK319347A (Compound 1) inhibits TBK1 enzyme (IC50: 93 nM), which also translates into good cell potency (72 nM). IKK-3 Inhibitor (Compound 13) is a novel IκB kinase 2 (IKK2) inhibitor (IC50 of 790 nM)[2].

Cas No.

862812-98-4

分子式

C22H19N3O5S2

分子量

469.53

储存和溶解度

DMSO:45 mg/mL (95.84 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years