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TBK1/IKKε-IN-1
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
TBK1/IKKε-IN-1图片
CAS NO:2058264-32-5
包装:5 mg
市场价:7000元

产品介绍

产品描述

TBK1/IKKε-IN-1 is a dual inhibitor of TBK1 and IKKε (IC50s of<100 nM).

体外活性

IKKε and TBK1 are serine/threonine kinases and are highly homologous to other IkB kinases (IKK-α and IKK-β). The two kinases play an integral role in the innate immune system. Double-stranded RNA viruses are recognized by Toll-like receptors 3 and 4 and RNA helicases RIG-1 and MDA-5, and lead to the activation of the TRIF-TBK1/IKKε-IRF3 signaling cascade, resulting in type I interferon. response.

Cas No.

2058264-32-5

分子式

C28H26N4O5

分子量

498.53

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years