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Broflanilide
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Broflanilide图片
CAS NO:1207727-04-5
包装与价格:
包装价格(元)
2 mg电议
5 mg电议
10 mg电议
25 mg电议
50 mg电议
100 mg电议
200 mg电议
500 mg电议
1 mL*10 mM(in DMSO)电议

产品介绍
Broflanilide 是昆虫抗狄氏剂 GABA 受体拮抗剂,可代谢为 Desmethyl-Broflanilide,抑制斜纹夜蛾 RDL GABAR,IC50值为 1.3 nM。

产品描述

Broflanilide is metabolized to desmethyl-broflanilide, which is a potent antagonist at the insect resistant-to-dieldrin GABA receptor and inhibits S. litura RDL GABAR with IC50 of 1.3 nM.

体外活性

Broflanilide is an insecticide and metabolized to desmethyl-broflanilide. Desmethyl-broflanilide shows weak activity against human GABAA α1β2γ2 receptor, the mammalian GABAA α1β3γ2 receptor and human glycine receptor (GlyR) α1β with IC50s >3 μM, and less potently inhibits GlyR α1-A288Gβ and GlyR α1-A288G with IC50s of 0.706 and 0.149 μM respectively.

Cas No.

1207727-04-5

分子式

C25H14BrF11N2O2

分子量

663.28

储存和溶解度

DMSO:225 mg/mL (339.22 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years