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Ligustilide
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Ligustilide图片
CAS NO:4431-01-0
包装与价格:
包装价格(元)
20 mg电议
1 mL*10 mM(in DMSO)电议

产品介绍
Ligustilide 是从当归和川芎中分离出来的一种生物活性邻苯二甲酸酯衍生物,具有神经保护、抗癌、抗炎和血管扩张作用。

产品描述

3-Butylidene-4,5-dihydrophthalide is an effective constituent extracted from Angelica sinensis.

体外活性

To investigate the neuroprotective of ligustilide (LIG) against glutamate-induced apoptosis of PC12 cells, cell viability were examined by MTT assay. Pretreatment with ligustilide (1, 5, 15 μmol · L(-1)) significantly improved cell viability. The apoptosis rate in glutamate-induced PC12 cells was 13.39%, and decreased in the presence of ligustilide (1, 5, 15 μmol · L(-1)) by 9.06%, 6.48%, 3.82%, separately. Extracellular accumulation of Ca2+ induced by glutamate were significantly reduced by ligustilide .

Cas No.

4431-01-0

分子式

C12H14O2

分子量

190.24

储存和溶解度

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years