Furafylline 是有选择性的人细胞色素P450IA2抑制剂(IC50:0.07 μM)。

Furafylline is a selective inhibitor of human cytochrome P450 (CYP)1A2 (IC50 : 0.07 μM),

Furafylline was a potent, non-competitive inhibitor of high affinity phenacetin O-deethylase activity of microsomal fractions of human liver, a reaction catalysed by P450IA2, with an IC50 value of 0.07 microM[1].

Furafylline was originally introduced as a bronchodilator with extended duration compared to theophylline[1].

80288-49-9

C12H12N4O3

260.253

呋喃茶碱;呋拉茶碱

DMSO:12.5 mg/mL (48.03 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years