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PtdIns-(3,4,5)-P3(1,2-dihexanoyl)(ammonium salt)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
PtdIns-(3,4,5)-P3(1,2-dihexanoyl)(ammonium salt)图片
CAS NO:799268-62-5
包装:1 mg
市场价:4321元

产品名称
PtdIns-(3,4,5)-P3 (1,2-dihexanoyl) (ammonium salt)
产品介绍

产品描述

The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns-(3,4,5)-P3, also known as PIP3, is resistant to cleavage by PI-specific phospholipase C (PLC). Thus, it is likely to function in signal transduction as a modulator in its own right, rather than as a source of inositol tetraphosphates. PIP3 can serve as an anchor for the binding of signal transduction proteins bearing pleckstrin homology (PH) domains. Protein binding to PIP3 is important for cytoskeletal rearrangement and membrane trafficking. PtdIns-(3,4,5)-P3 (1,2-dihexanoyl) is a synthetic analog of natural PIP3 with C6:0 fatty acids at the sn-1 and sn-2 positions. The compound features the same inositol and diacylglycerol (DAG) stereochemistry as that of the natural compound. The short fatty acid chains of this analog give it different physical properties from naturally-occurring PIP3, including higher solubility in aqueous media.

Cas No.

799268-62-5

分子式

C21H45NO22P4

分子量

787.47

别名

PtdIns-(3,4,5)-P3 (1,2-dihexanoyl) (ammonium salt)

储存和溶解度

H2O:10 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years