Biotin-PEG3-azide 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成
产品描述
Biotin-PEG3-azide is a PEG-based PROTAC linker can be used in PROTAC synthesis.
体外活性
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Cas No.
875770-34-6
分子式
C18H32N6O5S
分子量
444.55
别名
N-[2-[2-[2-(2-叠氮乙氧基)乙氧基]乙氧基]乙基]生物素胺
储存和溶解度
DMSO:10 mg/mL (22.49 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years