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Biotin-PEG3-acid
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Biotin-PEG3-acid图片
CAS NO:252881-76-8
包装与价格:
包装价格(元)
25 mg电议
50 mg电议
100 mg电议
200 mg电议

产品名称
18-[(3AS,4S,6AR)-六氢-2-氧代-1H-噻吩并[3,4-D]咪唑-4-基]-14-氧代-4,7,10-三氧杂-13-氮杂十八烷酸
产品介绍
Biotin-PEG3-acid 是一种属于 PEG 类的、生物素标记的 PROTAC linker,可用于 PROTAC 分子的合成。

产品描述

Biotin-PEG3-acid is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs.Biotin-PEG3-acid is a heterobiofunctional biotin PEG derivative containing a carboxylic acid group. The hydrophilic PEG spacer arm imparts water solubility that is transferred to the biotinylated molecule. PEG Linkers may be useful in the development of antibody drug conjugates and drug delivery methods.

体外活性

PROTACs contain two different ligands connected by a linker; one of them is a ligand for an E3 ubiquitin ligase and the other one is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Cas No.

252881-76-8

分子式

C19H33N3O7S

分子量

447.55

别名

18-[(3AS,4S,6AR)-六氢-2-氧代-1H-噻吩并[3,4-D]咪唑-4-基]-14-氧代-4,7,10-三氧杂-13-氮杂十八烷酸

储存和溶解度

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years