NH2-C5-NH-Boc 是一种属于 alkyl chain 类的 PROTAC linker,可用于 PROTAC 分子的合成。
产品描述
NH2-C5-NH-Boc (PROTAC Linker 23) is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
体外活性
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Cas No.
51644-96-3
分子式
C10H22N2O2
分子量
202.29
别名
PROTAC Linker 23;N-(5-氨基戊基)氨基甲酸叔丁酯
储存和溶解度
Ethanol:100 mg/mL (494.34 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years