SMCC-DM1 是一种药物-接头偶联物，由有效的微管破坏剂 DM1 和接头 SMCC 组成，用于制备抗体药物偶联物。

SMCC-DM1 (DM1-SMCC) is a drug-linker conjugate which composed of a potent microtubule-disrupting agent DM1 and a linker SMCC to make antibody-drug conjugate (ADC).

SMCC-DM1 inhibits HCC1954 and MDA-MB-468 cells proliferation with IC50s of 17.2 and 49.9 nM, respectively[1].

1228105-51-8

C51H66ClN5O16S

1072.61

DM1-SMCC

DMSO:90 mg/mL (83.91 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years