7-Acetoxy-4-methylcoumarin 是羧酸酯酶的荧光底物，在切割时会产生蓝色荧光溶液。该化合物已用于非质子介质（一种细胞膜环境模拟物），以研究分散在水介质中的模型生物膜的超氧化物和相关的氧自由基反应。由于 AChE 能够裂解和激活 7-Acetoxy-4-methylcoumarin，因此荧光底物已被用于研究 AChE 抑制剂 Tacrine·HCl (sc-200172)。该化合物也已从 Trigonella foenum graceum 中分离出来。

7-Acetoxy-4-methylcoumarin is a fluorogenic substrate for carboxylesterase yielding a blue fluorescent solution upon cleavage. The compound has been used in aprotic media, a cell membrane environmental mimic, to study superoxide and related oxyl-radical reactions of model biological membranes dispersed in aqueous media. Due to the ability for AchE to cleave and activate 7-Acetoxy-4-methylcoumarin, the fluorogenic substrate has been used to study the AchE inhibitor Tacrine·HCl (sc-200172). The compound has also been isolated from Trigonella foenum graceum.

2747-05-9

C12H10O4

218.208

7-乙酰氧基-4-甲基香豆素;MU-Ac

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years