4-Methylumbelliferyl-α-D-Galactopyranoside (4-MU-α-Gal)是α-半乳糖苷酶的荧光底物。除了用于表征新的α-半乳糖苷酶外,4-MU-α-Gal还用于评估与法布里病相关的α-半乳糖糖苷酶活性的缺乏。
产品描述
4-Methylumbelliferyl-α-D-Galactopyranoside (4-MU-α-Gal) is a fluorogenic substrate of α-galactosidase. In addition to its use in characterizing novel α-galactosidases, 4-MU-α-Gal is used in assays to evaluate deficiency in α-galactosidase activity related to Fabry disease.
体外活性
Hydrolysis of 4-MU-α-Gal releases the fluorescent product 4-MU, which has an emission maximum at 445-454 nm. The excitation maximum for 4-MU is pH-dependent: 330, 370, and 385 nm at pH 4.6, 7.4, and 10.4, respectively[1].
Cas No.
38597-12-5
分子式
C16H18O8
分子量
338.31
别名
4MU-α-Gal
储存和溶解度
DMF:45mg/mL (133mM)
DMSO:1 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years