RIPGBM 是一种选择性诱导多形性胶质母细胞瘤癌症的细胞凋亡诱导剂 ，EC50≤500 nM。

RIPGBM is a selective inducer of apoptosis in glioblastoma multiforme cancer stem cells (EC50: ≤500 nM).

RIPGBM causes caspase 1-dependent apoptosis by binding to receptor-interacting protein kinase 2 and acting as a molecular switch. It reduces the formation of a prosurvival RIPK2/ TAK1 complex and increases the formation of a proapoptotic RIPK2/caspase 1 complex [1].

355406-76-7

C26H21FN2O3

428.45

DMSO:30 mg/mL (70.02mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years