J14 是一种可逆的 sulfiredoxin 抑制剂，IC50=8.1 μM。它能够抑制sulfiredoxin诱导氧化应激，使细胞内ROS积累，导致细胞毒性和癌细胞死亡。

J-14 is an inhibitor of reversible sulfiredoxin(IC50 : 8.1 μM). J14 induces oxidative stress (intracellular ROS accumulation) by inhibiting sulfiredoxin, leading to cytotoxicity and cancer cell death

1043854-13-2

C28H25ClN4O2S

517.04

J-14

DMSO:260 mg/mL (502.86 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years