NSC622608 是 V 域 Ig 抑制 T 细胞活化 (VISTA) 的小分子配体，VISTA 是影响 T 细胞攻击肿瘤能力的免疫检查点。

NSC622608 is a small-molecule ligand for V-domain Ig suppressor of T-cell activation (VISTA) which is an immune checkpoint that affects the ability of T-cells to attack tumors.

NSC622608 blocked VISTA signaling in vitro, enhanced T-cell proliferation, and restored T-cell activation in the presence of VISTA-expressing cancer cell lines[1].

2593254-90-9

C9H12BrN3OS2

322.24

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years