Epidermal Growth Factor Receptor Peptide Acetate 存在于细胞表面，通过与其特异性配体的结合而被激活。EGFR 属于受体酪氨酸激酶 (RTK) 的 ErbB 家族。

Epidermal Growth Factor Receptor Peptide exists on the cell surface and is activated by the binding of its specific ligands.EGFR belongs to the ErbB family of receptor tyrosine kinases (RTK).

This autophosphorylation elicits downstream activation and signaling by several other proteins that associate with the phosphorylated tyrosines through their own phosphotyrosine-binding SH2 domains.?These downstream signaling proteins initiate several signal transduction cascades, principally the MAPK, Akt and JNK pathways, which lead to DNA synthesis and cell proliferation.Such proteins modulate phenotypes such as cell migration, adhesion, and proliferation.?Activation of the receptor is important for the innate immune response in human skin.?

T21723L

C63H97N13O25

1436.52

Epidermal Growth Factor Receptor Peptide Acetate(96249-43-3 Free base)

H2O:10 mg/mL (7.27mM)
DMSO:133mg/mL(96.62mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years