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LEESGGGLVQPGGSMK acetate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
LEESGGGLVQPGGSMK acetate图片
包装与价格:
包装价格(元)
5 mg电议
10 mg电议

产品介绍

产品描述

LEESGGGLVQPGGSMK acetate, a proteolysis peptide, is a component of Infliximab. LEESGGGLVQPGGSMK acetate can be used for quantitative analysis of Infliximab. Infliximab is a chimeric monoclonal IgG1 antibody that specifically binds to TNF-α[1].

体外活性

The anti-TNF antibodies blocking the action of TNF alpha revolutionized therapy of TNF-related diseases such as Inflammatory Bowel Disease, lupus, ulcerative colitis, ankylosing spondylitis, psoriatic arthritis and rheumatoid arthritis. The main anti-TNF antibodies that are currently authorized encompass Infliximab, Etanercept, Adalimumab, Certolizumab and Golimumab[1].

体内活性

By neutralizing TNF activity, anti-TNF antibodies promote mucosal healing and induce long-term remissions in vivo.

储存和溶解度

H2O:100 mg/mL (62.28 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years