PACAP (1-38), a novel neuropeptide isolated from the bovine hypothalamus is more active than vasoactive intestinal peptide (VIP) in stimulating adenylate cyclase (EC50=7 nM). PACAP 1-38 (10-9 M) increased substance P (SP), gastrin releasing peptide (GRP), and VIP release. PACAP 1-38 (10-8 M) inhibited gastrin secretion and stimulated somatostatin secretion and motility dose-dependently.

TP1054

C203H331N63O53S.C2HF3O2

4648.28

Pituitary Adenylate Cyclase Activating Polypeptide 38 (TFA)

H2O:Soluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years