MS48107 是 G 蛋白偶联受体 68 (GPR68) 的选择性正变构调节剂，对GPR68的选择性高于密切相关的神经递质转运蛋白，质子 GPCR和 HERG 离子通道。它可以穿越过小鼠的血脑屏障。

MS48107 is a potent and selective positive allosteric modulator of G protein-coupled receptor 68 (GPR68). It is selective for GPR68 over the closely related proton GPCRs, neurotransmitter transporters, and hERG ion channels. It can readily cross the blood-brain barrier (BBB) in mice.

2375070-79-2

C23H20FN5O2

417.44

Benzenemethanol, 2-[4-amino-6-[[(4-phenoxyphenyl)methyl]amino]-1,3,5-triazin-2-yl]-3-fluoro-

DMSO:100 mg/mL (239.56 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years