S1RA 是一种有效且特异性的sigma-1受体拮抗剂，Ki为17nM，对 σ2R 具有良好的选择性，Ki值大于 1000 nM。

S1RA(E-52862) is a potent and selective sigma-1 receptor(σ1R, Ki=17 nM) antagonist, showed good selectivity against σ2R (Ki >1000 nM).

878141-96-9

C20H23N3O2

337.423

4-(2-((5-甲基-1-(2-萘基)-1H-吡唑-3-基)氧基)乙基)吗啉;E-52862

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years