Myriocin is a fungal metabolite isolated from Myriococcum albomyces, Isaria sinclairi and Mycelia sterilia. Myriocin also is an effective inhibitor of serine-palmitoyl-transferase (SPT) and a key enzyme in de novo synthesis of sphingolipids. Myriocin strongly inhibits replication of both the subgenomic HCV-1b replicon and the JFH-1 strain of genotype 2a infectious HCV. It has an IC50 of 3.5 μg/mL for inhibiting HCV infection.

35891-70-4

C21H39NO6

401.54

DMSO:5 mg/mL (12.45 mM),ultrasonic and warming and heat to 60°C
Powder: -20°C for 3 years
In solvent: -80°C for 2 years