Neohesperidin 是一种类黄酮化合物,存在于葫芦科植物中,具有抗氧化和抗炎活性。
产品描述
Neohesperidin with antioxidant and neuroprotective properties. Unlike other citrus flavanones, it does not inhibit oral carcinogenesis in a rat model.
体内活性
Neohesperidin (50 mg/kg) markedly inhibits 55.0% of HCl/ethanol-induced gastric lesions. In pylorus ligated rats, neohesperidin (50 mg/kg) significantly decreases the volume of gastric secretion and gastric acid output, and increases the pH[1]. Treatment of neohesperidin significantly decreases fasting glucose, serum glucose, and glycosylated serum protein (GSP) in mice. It significantly elevates oral glucose tolerance and insulin sensitivity and decreases insulin resistance in the diabetic mice. Neohesperidin significantly decreases serum triglycerides, total cholesterol, leptin level, and liver index in the mice[3].
Cas No.
13241-33-3
分子式
C28H34O15
分子量
610.565
别名
新橙皮苷;NSC 31048;Hesperetin 7-O-neohesperidoside
储存和溶解度
DMSO:122 mg/mL (199.81 mM)
H2O:<1 mgml
Ethanol:<1 mgml
Powder: -20°C for 3 years
In solvent: -80°C for 2 years