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Tyk2-IN-3
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Tyk2-IN-3图片
CAS NO:1779493-12-7
包装:5 mg
市场价:7000元

产品介绍

产品描述

Tyk2-IN-3 is an inhibitor of Tyk2 pseudokinase (IC50: 485 nM).

体内活性

Tyk2-IN-3 is very potent Tyk2 pseudokinase against (99% inhibition at 1 μM) but lacks potency against all other kinases in the kinome assay panel except IKK (96% inhibition) and the JAK1 pseudokinase domain (99% inhibition at 1 μM). The pseudokinase domains of JAK2 and JAK3 are not part of the kinome screening panel. In the IL-23-stimulated kit225 T cell assay, Tyk2-IN-3 inhibits the stimulated response with an IC50 of 485±143 nM (n=3).

Cas No.

1779493-12-7

分子式

C25H24N6O3S2

分子量

520.63

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years