c-Fms-IN-6 is a potent inhibitor of c-FMS (IC50 ≤10 nM for unphosphorylated c-FMS) and also weakly inhibits unphosphorylated c-KIT and PDGFR (IC50: >1 μM).

c-Fms-IN-6 (Example 38) shows inhibitory activity against M-NFS-60 cell proliferation (IC50: 0.01 μM to 0.1 μM).

1628574-81-1

C22H25N7O2

419.48

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years