BCX 1470 methanesulfonate inhibits the esterolytic activity of factor D and C1s (IC50: 96 nM and 1.6 nM), 3.4- and 200-fold better than that of trypsin, respectively.

BCX 1470 methanesulfonate is an inhibitor serine protease. BCX 1470 blocks the esterolytic and hemolytic activities of the complement enzymes Cls and factor D in vitro.

BCX 1470 methanesulfonate blocked the development of RPA-induced edema in the rat.

217099-44-0

C15H14N2O5S3

398.48

DMSO:33.33 mg/mL (83.64 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years