4-Butylresorcinol 是苯酚衍生物,可以抑制酪氨酸酶,其IC50=11.27 μM。
产品描述
4-Butylresorcinol is a potent inhibitor of tyrosinase(IC50 : 11.27 μM), and is used in cosmetics as a depigmenting agent.
体外活性
4-Butylresorcinol (4-n-butylresorcinol) significantly inhibits melanin synthesis in a concentration-dependent manner. It is also found to inhibit the activity of tyrosinase, the rate-limiting melanogenic enzyme. 4-Butylresorcinol does not induce ERK, Akt activation, or MITF degradation, and has no effect on cAMP response element binding protein (CREB) phosphorylation, which stimulates MITF expression.
Cas No.
18979-61-8
分子式
C10H14O2
分子量
166.22
别名
4-丁基间苯二酚;4-正丁基间苯二酚;Butylresorcinol
储存和溶解度
DMSO:150 mg/mL (902.42 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years