产品描述
Imidaprilate is an active metabolite of TA-6366, acts as a potent angiotensin-converting enzyme (ACE) inhibitor (IC50: 2.6 nM). It is used in the research of the hypertensive disease.
体外活性
Imidaprilate augments the bradykinin-induced contraction of guinea pig ileum, with AC50 of 1.7 nM.Imidaprilate ?is an active metabolite of 6366, acts as a potent angiotensin converting enzyme (ACE) inhibitor, with an IC50 of 2.6 nM.
体内活性
Imidaprilate (≥0.2 mg/kg) inhibits angiotensin I (AT-I)-induced pressor response.
Cas No.
89371-44-8
分子式
C18H23N3O6
分子量
377.39
别名
6366A;Imidaprilat
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years