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AM-1638
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
AM-1638图片
CAS NO:1142214-62-7
包装与价格:
包装价格(元)
50 mg电议
100 mg电议

产品介绍

产品描述

AM-1638 is a full agonist of GPR40/FFA1 (EC50: 0.16 μM).

体内活性

AM-1638 exhibits moderate cross-species plasma clearance and volume of distribution, resulting in plasma half-lives suitable for evaluation of its antidiabetic properties in mouse, rat, and cynomologus monkey. AM-1638 exhibits antidiabetic activity in BDF/DIO mice[1]. Moreover, oral administration of full agonist AM-1638 demonstrates excellent oral bioavailability (mouse, >100%; rat, 72%; and cyno, 71%).

Cas No.

1142214-62-7

分子式

C33H35FO4

分子量

514.63

储存和溶解度

DMSO:250 mg/mL (485.79 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years