3-Chloro-5-hydroxybenzoic acid 是一种口服具有活力的乳酸受体GPR81选择性激动剂,对人 GPR81 的EC50为 16 μM。肥胖小鼠模型中,它表现出良好的体内脂肪分解作用。
产品描述
3-chloro-5-hydroxy Benzoic Acid (3-chloro-5-hydroxy BA) is an agonist of GPR81 (EC50 : 16 μM)
体内活性
3-chloro-5-hydroxybenzoic Acid is similarly effective at GPR81 receptors from a variety of mammalian species and is bioavailable, stimulating lipolysis (increased serum free fatty acids) in mice fed high fat chow for 10 weeks[1]
Cas No.
53984-36-4
分子式
C7H5ClO3
分子量
172.56
储存和溶解度
DMSO:34mg/mL(197.03mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years