Protirelin Acetate 是高度保守的神经肽，具有促甲状腺激素水平的激素控制作用，及神经调节的能力。

Protirelin Acetate is a thyrotropin-releasing hormone, stimulating the release of thyrotropin and prolactin from the anterior pituitary.

Protirelin (TRH) is an evolutionarily ancient neuropeptide, having its origin before the divergence of protostomes and deuterostomes that may ancestrally have been involved in the control of postembryonic growth and reproduction[1]. The effect of the thyrotropin-releasing hormone (Protirelin, TRH), one of the hypothalamic releasing hormones, on body temperature is investigated in the rat. Protirelin, in doses of 1, 5, 10 and 20 mg/kg, is injected intraperitoneally to male Wistar rats weighing 200-250 g. Protirelin causes a temporary rise in body temperature dose-dependently. The thyroidectomized rats injected 20 mg/kg of Protirelin which induces a significant hyperthermia in the sham-operated animals, fail to show a rise in body temperature. The present results suggest that a release of thyroid hormone might participate in the hyperthermic action of Protirelin[2].

120876-23-5

C38H56N12O14

904.936

TRH Acetate;TSH-RF Acetate;TRF Acetate;醋酸普罗瑞林

H2O:50 mg/mL (110.51 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years