MB-07811 是 MB07344 的一种口服活性 HepDirect 前药，具有降低胆固醇和甘油三酯的活性。 MB-07811 是肝脏靶向甲状腺激素受体-β 的激动剂。

MB-07811 is an orally active HepDirect prodrug of MB07344 with cholesterol and triglycerides lowering activity. MB-07811 is an agonist of liver-targeted THR-β.

MB-07811 has a low affinity for thyroid hormone receptors with a Ki of 14.6 μM for TRβ and a Ki of 12.5 μM for TRα[2].

In diet-induced obese mice, MB-07811 (0.3-30 mg/kg) decreases cholesterol and triglycerides[2].

852948-13-1

C28H32ClO5P

514.98

VK-2809

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years