Totarol 对几种致病性革兰氏阳性细菌、结核分枝杆菌具有抗菌作用。

Totarol shows antibacterial effects against several pathogenic Gram-positive bacteria, mycobacterium tuberculosis.

Totarol (2 μM) inhibits the proliferation of Bacillus subtilis cells and strongly induces the filamentation in B. subtilis cells. Totarol (1.5 μM) reduces the frequency of the Z-ring occurrence per micrometer of the bacterial cell length but did not affect the nucleoid frequency, suggesting that it blocks cytokinesis by inhibiting the formation of the Z-ring. Totarol perturbs the assembly dynamics of FtsZ protofilaments in the Z-ring[1].

511-15-9

C20H30O

286.45

(+)-Totarol;桃柁酚

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years