PCL 016 是一种局部抗病毒剂，可抑制兔体内的腺病毒复制。

2-Carboxypyridine is a topical antiviral agent, which inhibits adenovirus replication in rabbit.

Topical 1.5% PCL, 0.8% PCL, 0.369% PCL (pH7), 0.369% PCL (pH4) and 0.5% CDV are significantly more effective than the Control in reducing Ad Positive Cultures/Total (Days 1-14) and the Duration of Ad Shedding in the Ad5/NZW rabbit ocular model. Although not statistically significant, there appears to be a trend toward concentration-dependent efficacy of PCL 016 on the Duration of Ad Shedding. There is no apparent ocular toxicity associated with PCL 016 concentrations.

98-98-6

C6H5NO2

123.111

2-Picolinic acid;2-吡啶甲酸

H2O:50 mg/mL
DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years