GSK2330672 是高效的、不可吸收的、具有口服活性的顶端钠依赖性胆汁酸转运蛋白 (ASBT) 抑制剂，对人ASBT的IC50为 42 nM。它是一种降脂剂，具有用于 2 型糖尿病和原发性胆源性胆管炎的研究潜力。

GSK2330672 is a highly effective, nonabsorbable ASBT inhibitor (IC50: 42 ± 3 nM). It can lower glucose in an animal model of type 2 diabetes and shows excellent developability properties.

1345982-69-5

C28H38N2O7S

546.68

Iinerixibat;GSK2330672

DMSO:21.5 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years