S119-8 是一种广谱甲型和乙型流感病毒抑制剂，抑制多种乙型流感病毒和耐奥司他韦的甲型流感病毒。

RN-18 antagonizes Vif function and inhibits HIV-1 replication only in the presence of A3G. RN-18 increases cellular A3G levels in a Vif-dependent manner and increases A3G incorporation into virions without inhibiting general proteasome-mediated protein degradation. RN-18 enhances Vif degradation only in the presence of A3G, reduces viral infectivity by increasing A3G incorporation into virions and enhances cytidine deamination of the viral genome.

RN-18, that antagonizes Vif function and inhibits HIV-1 replication only in the presence of A3G.?RN-18 increases cellular A3G levels in a Vif-dependent manner and increases A3G incorporation into virions without inhibiting general proteasome-mediated protein degradation.?RN-18 enhances Vif degradation only in the presence of A3G, reduces viral infectivity by increasing A3G incorporation into virions and enhances cytidine deamination of the viral genome.

443639-96-1

C23H24N2O

344.45

DMSO:95 mg/mL (249.72 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years