Indinavir sulfate是一种 HIV 蛋白酶抑制剂。它抑制 HIV-1 蛋白酶，IC50 值为 0.41 nM，Ki 值为 0.24 nM。它也是SARS-CoV 3CLpro抑制剂，IC50为 1.71 μM。

Indinavir is a HIV protease inhibitor.It inhibits the HIV-1 protease with an IC50 value of 0.41 nM and Ki value of 0.24 nM.

At low concentrations (0.0003-10?μmol/l) indinavir acts as a positive allosteric modulator (EC50?=?0.021?μmol/l), whereas at concentrations greater than 10?μmol/l (30-100?μmol/l) indinavir acts as an inhibitor of the α7-nicotinic acetylcholine receptor.

157810-81-6

C36H49N5O8S

711.88

MK-639 sulfate;硫酸茚地那韦;L735524 sulfate

DMSO:100 mg/mL (140.48 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years