Aviptadil acetate 是模拟血管活性肠多肽类似物，具有血管舒张效应。它可诱导肺血管舒张并抑制血管 SMC 的增殖和血小板聚集。它可用于研究 SARS-CoV-2 引起的肺纤维化、肺动脉高压和呼吸衰竭。

Avitadil acetate induces pulmonary vasodilation and inhibits the proliferation of vascular SMCs and platelet aggregation. Avitadil acetate can be used for research on pulmonary fibrosis, pulmonary hypertension (PAH), and respiratory failure caused by SARS-CoV-2.

Aviptadil acetate inhibits the basal proliferation of pulmonary arterial smooth muscle cells (PASMC) and the mobilization of intracellular free calcium concentration in these cells in a dose-dependent manner[2].

Inhaled vasoactive intestinal peptide(Aviptadil acetate ) as a local therapy to reduce the alveolar inflammation found in patients with immune checkpoint inhibitor pneumonitis[1].

1444827-29-5

C147H238N44O42S.C2H4O2

3385.90

Vasoactive Intestinal Peptide acetate salt;醋酸阿肽地尔;阿肽地尔

DMSO:95mg/mL (28.06 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years