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Besifloxacin Hydrochloride
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Besifloxacin Hydrochloride图片
CAS NO:405165-61-9
包装与价格:
包装价格(元)
10 mg电议
50 mg电议
100 mg电议
200 mg电议

产品名称
BOL-303224-A
Besivance hydrochloride
盐酸贝西沙星
Besifloxacin HCl
产品介绍
Besifloxacin HCl是一种氟喹诺酮类抗生素。

产品描述

Besifloxacin HCl is a fourth-generation fluoroquinolone antibiotic.

体外活性

Besifloxacin has effectively bactericidal activity against prevalent and drug-resistant pathogens. Besifloxacin is the most potent agent tested against gram-positive pathogens and anaerobes and is generally equivalent to comparator fluoroquinolones in activity against most gram-negative pathogens. Besifloxacin demonstrates potent, broad-spectrum activity, which is particularly notable against gram-positive and gram-negative isolates that are resistant to other fluoroquinolones and classes of antibacterial agents.

激酶实验

20 ng of purified human DDK, together with increasing concentrations of each DDK inhibitor is pre-incubated for 5 min. Then 10 μCi (γ)-32P ATP and 1.5 μM cold ATP are added in a buffer containing 50 mM Tris-HCl (pH 7.5), 10 mM MgCl2, and 1 mM DTT and incubated for 30 min at 30°C. The proteins are denatured in 1X Laemmli buffer at 100°C followed by SDS-PAGE and autoradiography on HyBlot CL film. DDK kinase activity is indicated by Auto-phosphorylation of DDK. 32P-labeled bands are quantified using ImageJ and the IC50 values are calculated using GraphPad.

Cas No.

405165-61-9

分子式

C19H22Cl2FN3O3

分子量

430.3

别名

BOL-303224-A;Besivance hydrochloride;盐酸贝西沙星;Besifloxacin HCl

储存和溶解度

DMSO:10mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years