RO-0335 是新高效二苯醚非核苷逆转录酶抑制剂。它 (IC50= 1.1 nM) 可以抑制Wt HIV-1病毒,对 92% 的 NNRTI 耐药临床分离株具有保留活性 (IC50<100 nM)。
产品描述
RO-0335 is a potent diphenylether nonnucleoside reverse transcriptase inhibitor. RO-0335 inhibits Wt HIV-1 (IC50 = 1.1 nM) and retained activity (IC50< 100 nM) against 92% of a large number of NNRTI-resistant clinical isolates.
Cas No.
867365-76-2
分子式
C21H13BrCl2FN3O4S
分子量
573.21
储存和溶解度
DMSO:200mg/ml(348.91mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years