Lersivirine 是非核苷逆转录的抑制剂 (NNRTI)，有效抑制 NNRTI 耐药病毒。它对野生型人类免疫缺陷病毒和临床相关 NNRTI 耐药菌株显示出强大的抗逆转录病毒活性。

Lersivirine(UK 453061) is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) under development for HIV infection therapy.

473921-12-9

C17H18N4O2

310.357

3-氰基-5-[[3,5-二乙基-1-(2-羟基乙基)-1H-吡唑-4-基]氧基]苯腈;Lersivirine(UK 453061);UK-453061

DMSO:50 mg/mL (161.11 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years